Photochemistry and Photobiology
Our group focuses on discovering and understanding
fundamental relationships between molecular structure and photophysical behavior.
Because of their remarkable versatility, we are particularly interested in establishing
these correlations for archetype donor-acceptor dyes and their analogs. We use
these findings to develop improved chromophores for use in biophysical, biological
and medical applications such as single molecule detection, fluorescent reporting and
photodynamic therapy. Our approach encompasses nearly every aspect that is
essential to such an undertaking including computer-aided design, chemical synthesis,
photophysical characterization and in-vivo application of the resulting dyes.
Our group participates in collaborative research with many outstanding intramural
and extramural colleagues. We particularly enjoy sharing our expertise and
knowledge of dye chemistry with researchers inexperienced in that field.
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